Search results for "MOLECULAR MARKERS"

showing 10 items of 30 documents

Morphological, chemical, and genetic diversity of wild myrtle(Myrtus communis L.) populations in Sicily

2016

Myrtus communis L. İs a shrub widespread in the Mediterranean area. The interest in this species is growing, mainly due to its pharmacological and aromatic properties. The overexploitation of wild populations induced increasing degradation of plant cover with serious risk of loss of genetic diversity. This research explored the morphological, chemical, and genetic diversity of wild myrtle populations in Sicily, with the aim to provide a first characterization of a core collection of 36 accessions from 7 localities for future domestication programs. Amplified fragment length polymorphism fingerprinting generated 152 polymorphic fragments. STRUCTURE analysis identified three genetic clusters …

0106 biological sciences0301 basic medicineDPPHMyrtleBiology01 natural sciencesAnalysis of molecular varianceFixation index03 medical and health scienceschemistry.chemical_compoundleaf antioxidant propertieSettore AGR/07 - Genetica AgrariaBotanyDomesticationGenetic resourcesGenetic diversityABTSMyrtus communisEcologyLeaf antioxidant propertiesMolecular markersForestryAgronomySettore AGR/02 - Agronomia E Coltivazioni Erbacee030104 developmental biologyAmplified fragment length polymorphismgenetic resourcesleaf antioxidant propertiesmyrtlemolecular markersAmplified fragment length polymorphismchemistryAmplified fragment length polymorphismgenetic resourceAgronomi010606 plant biology & botanyFood ScienceTURKISH JOURNAL OF AGRICULTURE AND FORESTRY
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SILVOLIVE, a Germplasm Collection of Wild Subspecies With High Genetic Variability as a Source of Rootstocks and Resistance Genes for Olive Breeding

2020

15 páginas.- 5 figuras.- 1 tabla.- referencias.- The Supplementary Material for this article can be found online at: https://www.frontiersin.org/articles/10.3389/fpls.2020.00629/full#supplementary-material

0106 biological sciences0301 basic medicineGermplasmmolecular markersBranching[SDV]Life Sciences [q-bio]media_common.quotation_subjectPlant Sciencelcsh:Plant cultureBiologySubspecies01 natural sciencesAdaptabilityvigor03 medical and health sciencesgenetic variabilitybranchingwild germplasmlcsh:SB1-1110Genetic variabilityCultivarOlea europaeaComputingMilieux_MISCELLANEOUSmedia_commonHybridRootstocksOriginal ResearchGraftingMolecular markersfood and beverages15. Life on landrootstockbiology.organism_classificationgraftingHorticulture030104 developmental biologyOleaVigorGenetic variabilityRootstockWild germplasm010606 plant biology & botanyF30 Plant genetics and breeding
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In vitro propagation of the relict laperinne’s olive (Olea europaea L. subsp. laperrinei)

2017

Olea europaea L. subsp. laperrinei (Oleaceae) is an endemic taxon of the mountainous regions of central Sahara, consisting of currently fragmented and small relict populations. The tree can propagate vegetatively or by seed, but no recent natural regeneration was observed in the Algerian massive populations, some of which are considered threatened with extinction. Sterile triploid individuals were also identified in some populations showing increasing vigour. As a result of its long persistence and despite its rarity, the Laperrine's olive is an iconic component of Saharan mountain ecosystems. The aim of this study is to develop an efficient micropropagation protocol for both diploid and tr…

0106 biological sciences0301 basic medicinemicropropagationmolecular markerstriploidsPlant ScienceEndangered taxonolive tree01 natural sciences03 medical and health scienceschemistry.chemical_compoundMurashige and Skoog mediumBotanyEcology Evolution Behavior and Systematicsbiologyfungifood and beveragesbiology.organism_classificationthreatened germplasm030104 developmental biologyTaxonMicropropagationchemistryOleaOleaceaeShootThreatened speciesZeatin010606 plant biology & botany
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Permanent genetic resources added to molecular ecology resources database 1 April 2010 - 31 May 2010

2010

Correspondance: Molecular Ecology Resources Primer Development Consortium, E-mail: editorial.office@molecol.com; International audience; This article documents the addition of 396 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Anthocidaris crassispina, Aphis glycines, Argyrosomus regius, Astrocaryum sciophilum, Dasypus novemcinctus, Delomys sublineatus, Dermatemys mawii, Fundulus heteroclitus,Homalaspis plana, Jumellea rossii, Khaya senegalensis, Mugil cephalus, Neoceratitis cyanescens, Phalacrocorax aristotelis, Phytophthora infestans, Piper cordulatum, Pterocarpus indicus, Rana dalmatina, Rosa pulverulenta, Saxifraga …

0106 biological sciencesPiper marginatumPHYLOGENYSemecarpusMOLECULAR MARKERSECOLOGYcomputer.software_genre010603 evolutionary biology01 natural sciences03 medical and health sciencesLaboratorium voor PlantenveredelingRana ibericaREFERENCEMENTSPECIESPOPULATION GENETICSGENBANKBotanyGeneticsLife ScienceMICROSATELLITE MARKERmicrosatellite marker databasePiper cordulatumEcology Evolution Behavior and Systematics030304 developmental biology[SDV.EE]Life Sciences [q-bio]/Ecology environment0303 health sciencesbiologyDatabaseEPS-2Bioint Moleculair PhytopathologyTAXONOMY15. Life on landL10 - Génétique et amélioration des animauxbiology.organism_classificationJumelleaLaboratorium voor PhytopathologieFundulusPlant BreedingINSECTEMOLECULAR ECOLOGY RESOURCE DATABASECATALOGUELaboratory of PhytopathologyFundulus olivaceusJumellea rectaL20 - Écologie animaleGENETIQUE DES POPULATIONScomputerECOLOGIEBiotechnology
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Crocus sativus L. Ecotypes from Mediterranean Countries: Phenological, Morpho-Productive, Qualitative and Genetic Traits

2021

The characterization of C. sativus ecotypes is of great interest for preserving them from a possible genetic erosion due to the decrease of European cultivation surface. In this study, we evaluated four ecotypes from Italy (Sardinia and Abruzzo), Spain (Castilla-La Mancha), and Greece (Kozani) in order to detect the existence of variability and promote the biodiversity of this crop. Thirty-one traits related to saffron flowering, flower morphology, production of spice and daughter corms, vegetative development (leaf and corm traits), and spice quality, were evaluated. In addition, a genetic analysis through three PCR-based approaches, SSRs, RAPD, and SRAP was assessed. Results highlighted a…

0106 biological sciencesmolecular markersved/biology.organism_classification_rank.speciesBiodiversityAgronomiasaffronCormBiology01 natural sciencesCroplcsh:Agriculture03 medical and health sciencesCrocus sativusGenetic erosionCreixement (Plantes)030304 developmental biology0303 health sciencesEcotypeved/biologyPhenologylcsh:Scorm growthRAPDcrocinHorticultureflowering earlinessstigma yieldAgronomy and Crop ScienceCorm growth; Crocin; Flowering earliness; Molecular markers; Saffron; Stigma yield010606 plant biology & botany
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Genome-wide diversity and runs of homozygosity in the “Braque Français, type Pyrénées” dog breed

2018

Objective Braque Français, type Pyrénées is a French hunting-dog breed whose origin is traced back to old pointing gun-dogs used to assist hunters in finding and retrieving game. This breed is popular in France, but seldom seen elsewhere. Despite the ancient background, the literature on its genetic characterization is surprisingly scarce. A recent study looked into the demography and inbreeding using pedigree records, but there is yet no report on the use of molecular markers in this breed. The aim of this work was to genotype a population of Braque Français, type Pyrénées dogs with the high-density SNP array to study the genomic diversity of the breed. Results The average observed (\docum…

0301 basic medicineMalelcsh:MedicineRuns of HomozygosityGenetic diversitySettore AGR/17 - Zootecnica Generale E Miglioramento Geneticotype PyrénéesSNPGenetic diversityMolecular markersInbreedingRuns of homozygosityHeterozygosityEffective population sizeDogInbreedingDogBraque Français type PyrénéesSNPGenetic diversityMolecular markersInbreedingRuns of homozygosityHeterozygositylcsh:QH301-705.5education.field_of_studyHeterozygosityGenomeHomozygote04 agricultural and veterinary sciencesGeneral Medicinetype PyrénéesBraque Français type PyrénéesBreedResearch NoteFemaleFranceInbreedingSNP arrayGenetic MarkersHeterozygotePopulationSNPBiologyRuns of homozygosityPolymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesDogsAnimalsGenetic variabilityeducationlcsh:Science (General)Genetic diversityDogBraque Françaislcsh:R0402 animal and dairy sciencebraque françaisMolecular markersGenetic Variation040201 dairy & animal science030104 developmental biologylcsh:Biology (General)Evolutionary biologyDog Braque Français type Pyrénées SNP Genetic diversity Molecular markers Inbreeding Runs of homozygosity Heterozygositylcsh:Q1-390BMC Research Notes
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Gene Expression (mRNA) Markers for Differentiating between Malignant and Benign Follicular Thyroid Tumours

2017

Distinguishing between follicular thyroid cancer (FTC) and follicular thyroid adenoma (FTA) constitutes a long-standing diagnostic problem resulting in equivocal histopathological diagnoses. There is therefore a need for additional molecular markers. To identify molecular differences between FTC and FTA, we analyzed the gene expression microarray data of 52 follicular neoplasms. We also performed a meta-analysis involving 14 studies employing high throughput methods (365 follicular neoplasms analyzed). Based on these two analyses, we selected 18 genes differentially expressed between FTA and FTC. We validated them by quantitative real-time polymerase chain reaction (qRT-PCR) in an independe…

0301 basic medicinePathologyMicroarrayThyroid Glandlaw.inventionlawFollicular phaseGene expressionAdenocarcinoma Follicularfollicular thyroid adenoma; follicular thyroid cancer; gene expression; microarray; meta-analysisSpectroscopyPolymerase chain reactionOligonucleotide Array Sequence Analysisfollicular thyroid cancerGeneral MedicineCANCERComputer Science ApplicationsGene Expression Regulation NeoplasticCARCINOMASFUSION ONCOGENEmicroarrayNEOPLASMSmedicine.medical_specialtyMOLECULAR MARKERSASPIRATIONBiologyCatalysisCLASSIFICATIONArticleInorganic Chemistry03 medical and health sciencesNODULESADENOMASmedicineBiomarkers TumorHumansRNA MessengerThyroid NeoplasmsPhysical and Theoretical ChemistryFollicular thyroid cancerMolecular BiologyGeneGene Expression ProfilingOrganic ChemistryThyroid adenomaACVRL1medicine.diseaseMODELmeta-analysis030104 developmental biologyfollicular thyroid adenomaMutationgene expressionInternational Journal of Molecular Sciences
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Genetic instability in calamondin (Citrus madurensis Lour.) plants derived from somatic embryogenesis induced by diphenylurea derivative

2007

Somatic embryos were regenerated in vitro from calamondin style-stigma explants cultured in the presence of N (6)-benzylaminopurine (BAP) cytokinin and three synthetic phenylurea derivatives, N-(2-chloro-4-pyridyl)-N-phenylurea (4-CPPU), N-phenyl-N'-benzothiazol-6-ylurea (PBU) and N,N'-bis-(2,3-methilendioxyphenyl)urea (2,3-MDPU). The phenylurea derivative compounds tested at micromolar level (12 muM) were able to induce a percentage of responsive explants significantly higher from that obtained with BAP and hormone-free (HF) conditions. In order to verify the genetic stability of the regenerants, 27 plants coming from different embryogenic events were randomly selected from each different …

CitrusSomatic embryogenesisMutantPlant ScienceBiologyGenetic polymorphismsSomaclonal variationTissue Culture Techniqueschemistry.chemical_compoundGene Expression Regulation PlantBotanygenetic polymorphismmolecular markerPolymorphism GeneticMolecular markersGeneral MedicineSomaclonal variabilitybiology.organism_classificationMolecular biologyIn vitroCulture MediaRutaceaechemistryMutagenesisCytokininmutationAgronomy and Crop ScienceCarbanilidesDNAMutationsExplant culturePlant regeneration
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Genetic Improvement of Sweet Chestnut in Sicily (Castanea sativa Mill.) by the Selection of Superior Autochthonous Genotypes

2010

In Sicily, the chestnut (Castanea sativa Mill.) grows in limited areas of the South eastern Mt. Etna volcano and of the Northern Mountains, namely Madonie and Nebrodi. In the Island, chestnut can be considered as a neglected species, because of the modest importance recognized to it for horticultural and forestry exploitation. Recently, the Sicilian regional government founded the 'Horticultural Forestry' project to promote the cultivation of chestnut as possible fruit tree for local city farmer markets, where typical products are usually sold. The project was developed in five steps, carried out during three years by the Dipartimento di Colture Arboree of Palermo University: identification…

CoatbiologyRipeningclonal selection morphological traits molecular markers quality characteristicsHorticulturebiology.organism_classificationFagaceaeSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticultureGenetic distancePlant morphologySettore AGR/07 - Genetica AgrariaMicrosatelliteCultivarFruit tree
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Gefitinib in lung cancer therapy. Clinical results, predictive markers of response and future perspectives.

2009

Over the past few years, epidermal growth factor receptor has emerged as one of the most important targets in tumorgenesis and several drugs targeting signal transduction pathways have been developed. The first among these agents to be approved for the treatment of NSCLC was gefitinib, a potent, selective and reversible inhibitor of HER1/EGFR tyrosine kinase activity. The review summarizes its clinical development and the new therapeutic options, with particular focus on predictive markers of susceptibility to this drug.

DrugOncologyCancer Researchmedicine.medical_specialtyLung Neoplasmsmolecular markersmedia_common.quotation_subjectgefitinibAntineoplastic AgentsGefitinibcancer therapyGefitinibCarcinoma Non-Small-Cell LungInternal medicinetyrosine kinase inhibitorsmedicineAnimalsHumansgefitinib; non-small cell lung cancer (NSCLC); epidermal growth factor receptor (HER1/EGFR); tyrosine kinase inhibitors; target therapy; molecular markers; EGFR mutationsEpidermal growth factor receptorLung cancermedia_commonPharmacologyClinical Trials as Topicbiologybusiness.industrytarget therapymedicine.diseaseEGFR mutationsepidermal growth factor receptor (HER1/EGFR)ErbB Receptorsnon-small cell lung cancer (NSCLC)OncologyQuinazolinesbiology.proteinMolecular MedicineSignal transductionbusinessBiomarkersEgfr tyrosine kinaseSignal Transductionmedicine.drug
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